Extracellular matrix metalloproteinases around loose total hip prostheses
نویسندگان
چکیده
منابع مشابه
Lymphocyte response to polymethylmethacrylate in loose total hip prostheses.
We investigated the lymphocyte-mediated immune response to polymethylmethacrylate bone cement in 26 patients who had revision surgery for aseptic loosening of cemented total hip arthroplasties, at a mean time of seven years after the first replacement. We studied eight patients with cemented total hip arthroplasties which were not loose as controls. Patch tests to polymethylmethacrylate bone ce...
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Although total hip arthroplasty (THA) has provided good results for over forty years, the choice of the optimal bearing surface still remains controversial. Tribology is defined as “the branch of science and technology that deals with the study of friction, wear, and lubrication”.1 Tribology is fundamental to the function and long-term survival of orthopaedic implants. With the development of h...
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In two cases of infected total hip replacements, Peptococcus magnus was isolated in pure culture from the implant when it was removed. Fluorescent antibody and ELISA studies have shown that both patients developed an antibody response to this anaerobic coccus soon after the replacement operation. These results suggest that the organism is a true infective agent, which was probably responsible f...
متن کاملLubricin and smooth muscle α-actin-containing myofibroblasts in the pseudomembranes around loose hip and knee prostheses.
The objective was to evaluate the presence and distribution of the lubricating and anti-adhesion glycoprotein lubricin and cells containing the contractile isoform smooth muscle α-actin (SMA) in pseudomembranes around loose hip prostheses. Periprosthetic tissue was obtained at revision arthroplasty of eight aseptic, loose hip implants, and for comparison three loose knee prostheses. Immunohisto...
متن کاملTotal Hip Arthroplasty Matrix Metalloproteinase TIMP ANALYSIS OF MEMBRANE TYPE 1 - MATRIX METALLOPROTEINASE, MATRIX METALLOPROTEINASE-2 AND TISSUE INHIBITOR OF METALLOPROTEINSE-2 IN LOOSE HIP PERIPROSTHETIC CONNECTIVE TISSUES
Introduction: The biocompatibility of total hip prostheses has been the subject of debate for three decades, and currently it appears evident that the loosening of technically well inserted prostheses is in part due to cellular responses in periprosthetic connective tissues. Despite of intensive research, the precise biological mechanisms responsible for the loosening of total hip joints have n...
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ژورنال
عنوان ژورنال: Acta Orthopaedica Scandinavica
سال: 1994
ISSN: 0001-6470
DOI: 10.3109/17453679408995454